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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNB2 All Species: 26.97
Human Site: S448 Identified Species: 59.33
UniProt: Q92953 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92953 NP_004761.2 911 102563 S448 E R A K R N G S I V S M N L K
Chimpanzee Pan troglodytes XP_528164 911 102575 S448 E R A K R N G S I V S M N L K
Rhesus Macaque Macaca mulatta A4K2T1 529 58315 R78 F P G T R L G R L Q A A A S E
Dog Lupus familis XP_543042 858 96045 L403 L C C I A G V L V I A L P I P
Cat Felis silvestris
Mouse Mus musculus A6H8H5 907 102331 S448 E R A K R N G S I V S M N L K
Rat Rattus norvegicus Q63099 907 102077 S448 E R A K R N G S I V S M N L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507252 997 108259 S382 E R A K R N G S I V S M N M K
Chicken Gallus gallus XP_425704 863 96938 I409 V L V I A L P I P I I V N N F
Frog Xenopus laevis NP_001079256 898 102391 S448 E R A K R N G S I V S M N L K
Zebra Danio Brachydanio rerio XP_695259 820 92072 A371 T K F T S I P A S F W W A T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195169 1105 121957 S490 N R A K R D G S L V S L D M R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 20.8 62.9 N.A. 92.7 92.8 N.A. 46.3 63.8 70.2 63.7 N.A. N.A. N.A. N.A. 38.2
Protein Similarity: 100 99.8 32.7 72 N.A. 95.3 95.3 N.A. 56.7 72.7 78.6 73.1 N.A. N.A. N.A. N.A. 53.7
P-Site Identity: 100 100 13.3 0 N.A. 100 100 N.A. 93.3 6.6 100 0 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 33.3 33.3 N.A. 100 100 N.A. 100 20 100 13.3 N.A. N.A. N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 64 0 19 0 0 10 0 0 19 10 19 0 0 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 55 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 10 0 10 0 0 0 0 0 0 10 0 0 0 0 10 % F
% Gly: 0 0 10 0 0 10 73 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 10 0 10 55 19 10 0 0 10 10 % I
% Lys: 0 10 0 64 0 0 0 0 0 0 0 0 0 0 55 % K
% Leu: 10 10 0 0 0 19 0 10 19 0 0 19 0 46 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 55 0 19 0 % M
% Asn: 10 0 0 0 0 55 0 0 0 0 0 0 64 10 0 % N
% Pro: 0 10 0 0 0 0 19 0 10 0 0 0 10 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 64 0 0 73 0 0 10 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 10 0 0 64 10 0 64 0 0 10 0 % S
% Thr: 10 0 0 19 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 10 0 10 0 0 0 10 0 10 64 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _